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Overview & Proposed Solution

Our solution is based on a combination of different genes, rather than just one:

  • We aim at creating a gene therapy DNA vector VTvaf17 carrying SHH, CTNNB1, NOG, and WNT7A therapeutic genes for the treatment of alopecia;

  • Previous research results have shown that insufficient expression of proteins encoded by these genes are associated with the development of a spectrum of diseases, including, but not limited to, alopecia, autoimmune diseases, hereditary and acquired pathological conditions such as connective tissue damage, and other processes;

  • Therefore we believe that genetic constructs that provide expression of proteins encoded by a combination of those genes can be used to develop drugs for the prevention and treatment of alopecia;

  • The genetic constructions described above have been separately filed for patent and the respective strains have been deposited in an international depository.

General Information

  • Alopecia, commonly known as male pattern baldness in men, is a very common condition when excess male hormones (androgens) in hair follicles stop hair growth on the scalp;

  • There are only two approved drugs for the condition, but they have low response rates and side effects;

  • About 0.15% of people are affected at some point in time.

Further Advantages:

  • A very large number of potential customers across the world seeking to try alternative therapies

  • Little competition in the gene therapy space

  • With mainly over-the-counter products and generic therapies available outside of the gene therapy space, there is also a potential to capture the traditional market share

Market Trends & Projections

Market Size Growth Forecast (2018 – 2026)



  • According to the American Hair Loss Association, 95% of the hair loss in men is caused by androgenetic alopecia;

  • The Association also states that around 800 thousand people are undergoing some form of treatment for hair loss across the globe;

  • The rise in the geriatric population, increasing consumer awareness and growing hypertension and depression among the middle aged population are some of the factors driving the alopecia treatment market;

  • This condition is more common for people with autoimmune diseases such as hyperthyroidism, diabetes, and Down syndrome.

Projections of Sales in the first 5 Years


Assumptions and Rate Definitions:
Incidence Rate: Average percentage of disease occurrence across the population.

Diagnosed Population: Percentage of the population with a correctly diagnosed disease.
Patients seeking new therapy: Diagnosed patients that are actively searching for alternative remedies for their illness; and are able and willing to undergo a new treatment.

Compliance rate: Out of the patients, who are actively seeking an alternative therapy, it is the percentage that actually make the switch and select a new therapy.

Patent information:

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